WebJul 1, 1982 · The results support the conclusion that altered activity in CMH nociceptors is a major peripheral determinant of cutaneous hyperalgesia following a mild heat injury to the skin. Discover the world ... WebBackground. Remifentanil-induced secondary hyperalgesia has been documented experimentally in both animals and healthy human volunteers, but never clinically. This study tested the hypotheses that increased pain sensitivity assessed by periincisional allodynia and hyperalgesia can occur after relatively large-dose intraoperative remifentanil and …
Hyperpathia, Hyperalgesia, and Hypersensitivity - Verywell …
WebDr. Lowe specializes in the treatment of cutaneous malignancies including melanoma, basal cell carcinoma and Merkel cell carcinoma. Disease Team Lead and Co-Chair, … WebAbstract. The intradermal injection of adenosine produces a dose-dependent decrease in mechanical nociceptive threshold in the hindpaw of the rat that is not attenuated by elimination of indirect pathways for the production of hyperalgesia. Adenosine-induced hyperalgesia is mimicked by the A2-agonists, 5'- (N-ethyl)-carboxamido-adenosine and … photoaccess director
CUTANEOUS HYPERALGESIA British Medical Bulletin Oxford …
WebAntinym: hypoalgesia (decreased pain sensitivity). Increased pain sensitivity at a site of tissue damage is called primary hyperalgesia. Increased pain sensitivity in normal skin surrounding a site of tissue damage is called secondary hyperalgesia. Hyperalgesia was traditionally defined as the psychophysical correlate of sensitization (either ... WebBackground. The anticonvulsant gabapentin, proven effective for neuropathic pain in two large, placebo-controlled clinical trials, is widely used for treatment of chronic pain. Preclinical studies have … WebAbstract. A method to measure cutaneous hyperalgesia to thermal stimulation in unrestrained animals is described. The testing paradigm uses an automated detection of … photoactivated definition