WebNational Center for Biotechnology Information WebJun 27, 2024 · Pectin, a complex polysaccharide in plant cell wall, mainly consists of four major types of polysaccharides: homogalacturonan, xylogalacturonan, rhamnogalacturonan I and II, all of which can be degraded into various pectin oligosaccharides (POS) and may provide abundant resource for exploring potential anticancer drugs.
Pectin: A Bioactive Food Polysaccharide with Cancer Preventive …
WebThe beneficial effects of cimetidine in the treatment of colon cancer are well documented. These effects probably arise from the multiple actions of cimetidine as an H2 receptor antagonist, an immunomodulator and as an inhibitor of adhesion molecule expression, but it is not yet approved by the FDA for use in these diseases. WebApr 1, 2010 · This study examines the effects of modified citrus pectin and QC on the size and weight of colon-25 tumors implanted in balb-c mice. Fifty mice were orally administered either 1 ml distilled water (controls), low-dose QC, high-dose QC, low-dose modified citrus pectin (0. 8 mg/ml) or high-dose modified citrus pectin (1.6 mg/ml) on a daily basis ... hiking denali peak
Characterization, biological evaluation and molecular docking of ...
WebJun 12, 2024 · Colorectal cancer (CRC) is the second cause of cancer death worldwide. The composition and enzymatic activity of colonic microbiota can significantly affect the effectiveness of CRC chemotherapy. Irinotecan is a drug widely used to treat colon cancer. However, the transformation of a drug-glucuronide (SN-38G) back to its active form (SN … WebAug 28, 2024 · Bananas contain pectin, which can reduce diarrhea and has been shown to protect against colon cancer in test-tube studies. 4. Grapefruit Grapefruit is a nutritious fruit loaded with... WebJun 12, 2024 · Both pectins were revealed to possess anticancer activity against human colorectal carcinoma HCT 116 cells ( Figure 1 A,B), as shown by the results of SRB as well … hiking denali safe